Model Comparison
Claude Opus 4.5 vs Mistral Large 3 (675B Instruct 2512 NVFP4)Which is better in 2026?
Claude Opus 4.5 significantly outperforms across most benchmarks.
Verdict: Claude Opus 4.5 vs Mistral Large 3 (675B Instruct 2512 NVFP4) — which is better?
Claude Opus 4.5 (by Anthropic) and Mistral Large 3 (675B Instruct 2512 NVFP4) (by Mistral AI) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.
Claude Opus 4.5 outperforms in 2 benchmarks (GPQA, MMMLU), while Mistral Large 3 (675B Instruct 2512 NVFP4) is better at 0 benchmarks. Claude Opus 4.5 significantly outperforms across most benchmarks.
Choose Claude Opus 4.5 if…
- you want the strongest raw capability — it leads on 2 of 2 shared benchmarks
Choose Mistral Large 3 (675B Instruct 2512 NVFP4) if…
- you want the most recent training data — it shipped Dec 2025
- you need open weights you can self-host or fine-tune
Performance Benchmarks
Comparative analysis across standard metrics
Claude Opus 4.5 outperforms in 2 benchmarks (GPQA, MMMLU), while Mistral Large 3 (675B Instruct 2512 NVFP4) is better at 0 benchmarks.
Claude Opus 4.5 significantly outperforms across most benchmarks.
Arena Performance
Human preference votes
Context Window
Maximum input and output token capacity
Only Claude Opus 4.5 specifies input context (200,000 tokens). Only Claude Opus 4.5 specifies output context (64,000 tokens).
Input Capabilities
Supported data types and modalities
Both Claude Opus 4.5 and Mistral Large 3 (675B Instruct 2512 NVFP4) support multimodal inputs.
They are both capable of processing various types of data, offering versatility in application.
Claude Opus 4.5
Mistral Large 3 (675B Instruct 2512 NVFP4)
License
Usage and distribution terms
Claude Opus 4.5 is licensed under a proprietary license, while Mistral Large 3 (675B Instruct 2512 NVFP4) uses Apache 2.0.
License differences may affect how you can use these models in commercial or open-source projects.
Proprietary
Closed source
Apache 2.0
Open weights
Release Timeline
When each model was launched
Claude Opus 4.5 was released on 2025-11-24, while Mistral Large 3 (675B Instruct 2512 NVFP4) was released on 2025-12-04.
Mistral Large 3 (675B Instruct 2512 NVFP4) is 0 month newer than Claude Opus 4.5.
Nov 24, 2025
6 months ago
Dec 4, 2025
6 months ago
1w newerKnowledge Cutoff
When training data ends
Claude Opus 4.5 has a documented knowledge cutoff of 2025-03-31, while Mistral Large 3 (675B Instruct 2512 NVFP4)'s cutoff date is not specified.
We can confirm Claude Opus 4.5's training data extends to 2025-03-31, but cannot make a direct comparison without Mistral Large 3 (675B Instruct 2512 NVFP4)'s cutoff date.
Mar 2025
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Outputs Comparison
Key Takeaways
Claude Opus 4.5
View detailsAnthropic
Detailed Comparison
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FAQ
Common questions about Claude Opus 4.5 vs Mistral Large 3 (675B Instruct 2512 NVFP4).
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