Model Comparison

Claude Sonnet 4.5 vs MedGemma 4B IT

Comparing Claude Sonnet 4.5 and MedGemma 4B IT across benchmarks, pricing, and capabilities.

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Performance Benchmarks

Comparative analysis across standard metrics

No common benchmarks found

Claude Sonnet 4.5 and MedGemma 4B IT don't have any common benchmark datasets to compare. They may have been evaluated on different testing suites.

Arena Performance

Human preference votes

Context Window

Maximum input and output token capacity

Only Claude Sonnet 4.5 specifies input context (200,000 tokens). Only Claude Sonnet 4.5 specifies output context (64,000 tokens).

Anthropic
Claude Sonnet 4.5
Input200,000 tokens
Output64,000 tokens
Google
MedGemma 4B IT
Input- tokens
Output- tokens
Mon May 25 2026 • llm-stats.com

Input Capabilities

Supported data types and modalities

Both Claude Sonnet 4.5 and MedGemma 4B IT support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

Claude Sonnet 4.5

Text
Images
Audio
Video

MedGemma 4B IT

Text
Images
Audio
Video

License

Usage and distribution terms

Claude Sonnet 4.5 is licensed under a proprietary license, while MedGemma 4B IT uses Health AI Developer Foundations terms of use.

License differences may affect how you can use these models in commercial or open-source projects.

Claude Sonnet 4.5

Proprietary

Closed source

MedGemma 4B IT

Health AI Developer Foundations terms of use

Open weights

Release Timeline

When each model was launched

Claude Sonnet 4.5 was released on 2025-09-29, while MedGemma 4B IT was released on 2025-05-20.

Claude Sonnet 4.5 is 4 months newer than MedGemma 4B IT.

Claude Sonnet 4.5

Sep 29, 2025

7 months ago

4mo newer
MedGemma 4B IT

May 20, 2025

1.0 years ago

Knowledge Cutoff

When training data ends

Claude Sonnet 4.5 has a documented knowledge cutoff of 2025-01-31, while MedGemma 4B IT's cutoff date is not specified.

We can confirm Claude Sonnet 4.5's training data extends to 2025-01-31, but cannot make a direct comparison without MedGemma 4B IT's cutoff date.

Claude Sonnet 4.5

Jan 2025

MedGemma 4B IT

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Outputs Comparison

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Key Takeaways

Anthropic
Larger context window (200,000 tokens)
Google
Has open weights

Detailed Comparison

AI Model Comparison Table
Feature
Anthropic
Claude Sonnet 4.5
Google
MedGemma 4B IT

FAQ

Common questions about Claude Sonnet 4.5 vs MedGemma 4B IT.

Which is better, Claude Sonnet 4.5 or MedGemma 4B IT?

Claude Sonnet 4.5 (Anthropic) and MedGemma 4B IT (Google) each have strengths in different areas. Compare their benchmark scores, pricing, context windows, and capabilities above to determine which fits your needs.

How does Claude Sonnet 4.5 compare to MedGemma 4B IT in benchmarks?

Claude Sonnet 4.5 scores MMMLU: 89.1%, AIME 2025: 87.0%, TAU-bench Retail: 86.2%, GPQA: 83.4%, MMMUval: 77.8%. MedGemma 4B IT scores MIMIC CXR: 88.9%, DermMCQA: 71.8%, PathMCQA: 69.8%, SlakeVQA: 62.3%, VQA-Rad: 49.9%.

What are the context window sizes for Claude Sonnet 4.5 and MedGemma 4B IT?

Claude Sonnet 4.5 supports 200K tokens and MedGemma 4B IT supports an unknown number of tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between Claude Sonnet 4.5 and MedGemma 4B IT?

Key differences include licensing (Proprietary vs Health AI Developer Foundations terms of use). See the full comparison above for benchmark-by-benchmark results.

Who makes Claude Sonnet 4.5 and MedGemma 4B IT?

Claude Sonnet 4.5 is developed by Anthropic and MedGemma 4B IT is developed by Google.