GPQA Biology

Biology subset of GPQA, containing challenging multiple-choice questions written by domain experts in biology. These Google-proof questions require graduate-level knowledge and reasoning.

o1 from OpenAI currently leads the GPQA Biology leaderboard with a score of 0.692 across 1 evaluated AI models.

Paper
About this benchmark

What GPQA Biology measures

GPQA Biology is a text benchmark that evaluates large language models on reasoning, general, healthcare, and biology tasks. LLM Stats tracks 1 model on this benchmark, with a maximum possible score of 1. Current average across reported models is 0.7, with the leader reaching 0.7.

Compare leaders on the best AI for reasoning, best AI for general, best AI for healthcare and best AI for biology leaderboards.

Publication

Paper
GPQA: A Graduate-Level Google-Proof Q&A Benchmark
Authors
David Rein, Betty Li Hou, Asa Cooper Stickland, Jackson Petty, and 4 others
Published

Abstract

We present GPQA, a challenging dataset of 448 multiple-choice questions written by domain experts in biology, physics, and chemistry. We ensure that the questions are high-quality and extremely difficult: experts who have or are pursuing PhDs in the corresponding domains reach 65% accuracy (74% when discounting clear mistakes the experts identified in retrospect), while highly skilled non-expert validators only reach 34% accuracy, despite spending on average over 30 minutes with unrestricted access to the web (i.e., the questions are "Google-proof"). The questions are also difficult for state-of-the-art AI systems, with our strongest GPT-4 based baseline achieving 39% accuracy. If we are to use future AI systems to help us answer very hard questions, for example, when developing new scientific knowledge, we need to develop scalable oversight methods that enable humans to supervise their outputs, which may be difficult even if the supervisors are themselves skilled and knowledgeable. The difficulty of GPQA both for skilled non-experts and frontier AI systems should enable realistic scalable oversight experiments, which we hope can help devise ways for human experts to reliably get truthful information from AI systems that surpass human capabilities.

OpenAIo1 leads with 69.2%.

Progress Over Time

Interactive timeline showing model performance evolution on GPQA Biology

State-of-the-art frontier
Open
Proprietary

GPQA Biology Leaderboard

1 models
ContextCostLicense
1
OpenAI
OpenAI
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FAQ

Common questions about GPQA Biology.

What is the GPQA Biology benchmark?

Biology subset of GPQA, containing challenging multiple-choice questions written by domain experts in biology. These Google-proof questions require graduate-level knowledge and reasoning.

What is the GPQA Biology leaderboard?

The GPQA Biology leaderboard ranks 1 AI models based on their performance on this benchmark. Currently, o1 by OpenAI leads with a score of 0.692. The average score across all models is 0.692.

What is the highest GPQA Biology score?

The highest GPQA Biology score is 0.692, achieved by o1 from OpenAI.

How many models are evaluated on GPQA Biology?

1 models have been evaluated on the GPQA Biology benchmark, with 0 verified results and 1 self-reported results.

Where can I find the GPQA Biology paper?

The GPQA Biology paper is available at https://arxiv.org/abs/2311.12022. The paper details the methodology, dataset construction, and evaluation criteria.

What categories does GPQA Biology cover?

GPQA Biology is categorized under reasoning, general, healthcare, and biology. The benchmark evaluates text models.

How recent are the GPQA Biology leaderboard results?

The GPQA Biology leaderboard was last updated in June 2026 and currently includes 1 evaluated models.

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