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Claude Sonnet 5.5 vs MedGemma 4B IT

Claude Sonnet 5.5 leads the LLM Stats Score 58.4 to -4.8.

Anthropic · Google · Updated for 2026

Which is better?

Claude Sonnet 5.5 leads the overall LLM Stats Score 58.4 to -4.8, ranking #2 overall.

Based on current LLM Stats indexes, shared benchmarks, pricing, and model metadata for 2026.

Choose Claude Sonnet 5.5

  • overall performance matters — it scores 58.4 and ranks #2 on LLM Stats
  • your work emphasizes reasoning — it leads those capability indexes
  • you want the most recent training data — it shipped Sep 2026

Choose MedGemma 4B IT

  • you need open weights you can self-host or fine-tune

At a glance

The differences that matter most.

Claude Sonnet 5.5
Anthropic
MedGemma 4B IT
Google
Core performance indexes
LLM Stats Score
58.4
#2
-4.8
#374
Reasoning
57.2
#3
-5.2
#370
Cost, coverage & limits
Benchmark wins
—
—
Input price
$2.00 / M
— / M
Output price
$10.00 / M
— / M
Context window
1,000,000
—

Capability indexes

Additional strengths measured across groups of related public benchmarks

2 shared
Index
Claude Sonnet 5.5
MedGemma 4B IT
Vision
41.5#2
-6.8#224
Multimodal
41.1#2
-5.5#183
Conservative TrueSkill rating · higher is betterHow scores work

Individual benchmarks

47 reported for Claude Sonnet 5.5 · 7 for MedGemma 4B IT

No common benchmarks found

Claude Sonnet 5.5 and MedGemma 4B ITdon't have any common benchmark datasets to compare. They may have been evaluated on different testing suites.

Human preference

Blind head-to-head votes and playground preference scores

Context Window

Maximum input and output token capacity

Only Claude Sonnet 5.5 specifies input context (1,000,000 tokens). Only Claude Sonnet 5.5 specifies output context (128,000 tokens).

Anthropic
Claude Sonnet 5.5
Input1,000,000 tokens
Output128,000 tokens
Google
MedGemma 4B IT
Input- tokens
Output- tokens
Fri Oct 23 2026 • llm-stats.com

Input capabilities

Documented input modalities across available providers

Both Claude Sonnet 5.5 and MedGemma 4B IT support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

Claude Sonnet 5.5

Text
Images
Audio
Video

MedGemma 4B IT

Text
Images
Audio
Video

License

Usage and distribution terms

Claude Sonnet 5.5 is licensed under a proprietary license, while MedGemma 4B IT uses Health AI Developer Foundations terms of use.

License differences may affect how you can use these models in commercial or open-source projects.

Claude Sonnet 5.5

Proprietary

Closed source

MedGemma 4B IT

Health AI Developer Foundations terms of use

Open weights

Release Timeline

When each model was launched

Claude Sonnet 5.5 was released on 2026-09-28, while MedGemma 4B IT was released on 2025-05-20.

Claude Sonnet 5.5 is 17 months newer than MedGemma 4B IT.

Claude Sonnet 5.5

Sep 28, 2026

3 weeks ago

1.4yr newer
MedGemma 4B IT

May 20, 2025

1.4 years ago

Knowledge Cutoff

When training data ends

Claude Sonnet 5.5 has a documented knowledge cutoff of 2026-06-01, while MedGemma 4B IT's cutoff date is not specified.

We can confirm Claude Sonnet 5.5's training data extends to 2026-06-01, but cannot make a direct comparison without MedGemma 4B IT's cutoff date.

Claude Sonnet 5.5

Jun 2026

MedGemma 4B IT

—

Outputs Comparison

Notice missing or incorrect data?

Judge for yourself.

Run your own prompts against Claude Sonnet 5.5 and MedGemma 4B IT side-by-side, then vote on the output you prefer.

Claude Sonnet 5.5
✓ Preferred
MedGemma 4B IT
Open in Playground

FAQ

Common questions about Claude Sonnet 5.5 vs MedGemma 4B IT.

Which is better, Claude Sonnet 5.5 or MedGemma 4B IT?

Claude Sonnet 5.5 leads the LLM Stats Score 58.4 to -4.8. Claude Sonnet 5.5 is made by Anthropic and MedGemma 4B IT is made by Google. The best choice depends on your use case — compare their capability indexes, individual benchmarks, pricing, and limits above.

How does Claude Sonnet 5.5 compare to MedGemma 4B IT in benchmarks?

Claude Sonnet 5.5 scores BenchCAD (with Python tool): 96.3%, ArXivMath (with tools): 95.2%, Global-MMLU: 92.1%, MILU: 91.6%, SWE-bench Multilingual: 90.3%. MedGemma 4B IT scores MIMIC CXR: 88.9%, DermMCQA: 71.8%, PathMCQA: 69.8%, SlakeVQA: 62.3%, VQA-Rad: 49.9%.

What are the context window sizes for Claude Sonnet 5.5 and MedGemma 4B IT?

Claude Sonnet 5.5 supports 1.0M tokens and MedGemma 4B IT supports an unknown number of tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between Claude Sonnet 5.5 and MedGemma 4B IT?

Key differences include LLM Stats Score (58.4 vs -4.8), licensing (Proprietary vs Health AI Developer Foundations terms of use). See the full comparison above for benchmark-by-benchmark results.

Who makes Claude Sonnet 5.5 and MedGemma 4B IT?

Claude Sonnet 5.5 is developed by Anthropic and MedGemma 4B IT is developed by Google.

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