Model Comparison

Gemma 4 E2B vs MedGemma 4B ITWhich is better in 2026?

Gemma 4 E2B significantly outperforms across most benchmarks.

Verdict: Gemma 4 E2B vs MedGemma 4B IT — which is better?

Gemma 4 E2B (by Google) and MedGemma 4B IT (by Google) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.

Gemma 4 E2B outperforms in 1 benchmarks (MedXpertQA), while MedGemma 4B IT is better at 0 benchmarks. Gemma 4 E2B significantly outperforms across most benchmarks.

Choose Gemma 4 E2B if…

  • you want the strongest raw capability — it leads on 1 of 1 shared benchmarks
  • you want the most recent training data — it shipped Apr 2026

Choose MedGemma 4B IT if…

  • you are already invested in the Google ecosystem

Performance Benchmarks

Comparative analysis across standard metrics

1 benchmarks

Gemma 4 E2B outperforms in 1 benchmarks (MedXpertQA), while MedGemma 4B IT is better at 0 benchmarks.

Gemma 4 E2B significantly outperforms across most benchmarks.

Sat Jul 25 2026 • llm-stats.com

Arena Performance

Human preference votes

Model Size

Parameter count comparison

800.0M diff

Gemma 4 E2B has 0.8B more parameters than MedGemma 4B IT, making it 18.6% larger.

Google
Gemma 4 E2B
5.1Bparameters
Google
MedGemma 4B IT
4.3Bparameters
5.1B
Gemma 4 E2B
4.3B
MedGemma 4B IT

Input Capabilities

Supported data types and modalities

Both Gemma 4 E2B and MedGemma 4B IT support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

Gemma 4 E2B

Text
Images
Audio
Video

MedGemma 4B IT

Text
Images
Audio
Video

License

Usage and distribution terms

Gemma 4 E2B is licensed under Apache 2.0, while MedGemma 4B IT uses Health AI Developer Foundations terms of use.

License differences may affect how you can use these models in commercial or open-source projects.

Gemma 4 E2B

Apache 2.0

Open weights

MedGemma 4B IT

Health AI Developer Foundations terms of use

Open weights

Release Timeline

When each model was launched

Gemma 4 E2B was released on 2026-04-02, while MedGemma 4B IT was released on 2025-05-20.

Gemma 4 E2B is 11 months newer than MedGemma 4B IT.

Gemma 4 E2B

Apr 2, 2026

3 months ago

10mo newer
MedGemma 4B IT

May 20, 2025

1.2 years ago

Knowledge Cutoff

When training data ends

Gemma 4 E2B has a documented knowledge cutoff of 2025-01-01, while MedGemma 4B IT's cutoff date is not specified.

We can confirm Gemma 4 E2B's training data extends to 2025-01-01, but cannot make a direct comparison without MedGemma 4B IT's cutoff date.

Gemma 4 E2B

Jan 2025

MedGemma 4B IT

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Outputs Comparison

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Key Takeaways

Google
Higher MedXpertQA score (23.5% vs 18.8%)
Google

No standout differentiators in the data we have for this pair.

Detailed Comparison

Interactive Arena

Judge for yourself.

Run your own prompts against Gemma 4 E2B and MedGemma 4B IT side-by-side, then vote on the output you prefer.

Gemma 4 E2B
✓ Preferred
MedGemma 4B IT
Open in Playground
AI Model Comparison Table
Feature
Google
Gemma 4 E2B
Google
MedGemma 4B IT

FAQ

Common questions about Gemma 4 E2B vs MedGemma 4B IT.

Which is better, Gemma 4 E2B or MedGemma 4B IT?

Gemma 4 E2B significantly outperforms across most benchmarks. Gemma 4 E2B is made by Google and MedGemma 4B IT is made by Google. The best choice depends on your use case — compare their benchmark scores, pricing, and capabilities above.

How does Gemma 4 E2B compare to MedGemma 4B IT in benchmarks?

Gemma 4 E2B scores MMMLU: 67.4%, MMLU-Pro: 60.0%, MathVision: 52.4%, MMMU-Pro: 44.2%, LiveCodeBench v6: 44.0%. MedGemma 4B IT scores MIMIC CXR: 88.9%, DermMCQA: 71.8%, PathMCQA: 69.8%, SlakeVQA: 62.3%, VQA-Rad: 49.9%.

What are the main differences between Gemma 4 E2B and MedGemma 4B IT?

Key differences include licensing (Apache 2.0 vs Health AI Developer Foundations terms of use). See the full comparison above for benchmark-by-benchmark results.

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