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Protein Design — Sequence Generation

Progress Over Time

Interactive timeline showing model performance evolution on Protein Design — Sequence Generation

State-of-the-art frontier
Open
Proprietary

Protein Design — Sequence Generation Leaderboard

2 models
ContextCostLicense
1—1.0M$2.00 / $10.00
2
Anthropic
Anthropic
—1.0M$0.10 / $0.50
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About this benchmark

What is Protein Design — Sequence Generation?

Protein design Sequence Generation task: generate novel protein sequences conditioned on design constraints.

Protein Design — Sequence Generation is a text benchmark evaluating models on science and biology tasks. LLM Stats tracks 2 models on this benchmark, scored on a 0–1 scale. The current average is 0.4, with the leader at 0.5.

Compare leaders on the best AI for science and best AI for biology leaderboards.

Current leaders

Claude Sonnet 5.5 from Anthropic currently leads the Protein Design — Sequence Generation leaderboard with a score of 0.510 across 2 evaluated AI models.

1Claude Sonnet 5.5Anthropic51.0%
2Claude Haiku 5.5Anthropic33.1%

FAQ

Common questions about the Protein Design — Sequence Generation benchmark and leaderboard.

What is the Protein Design — Sequence Generation benchmark?

Protein design Sequence Generation task: generate novel protein sequences conditioned on design constraints.

What is the Protein Design — Sequence Generation leaderboard?

The Protein Design — Sequence Generation leaderboard ranks 2 AI models based on their performance on this benchmark. Currently, Claude Sonnet 5.5 by Anthropic leads with a score of 0.510. The average score across all models is 0.420.

What is the highest Protein Design — Sequence Generation score?

The highest Protein Design — Sequence Generation score is 0.510, achieved by Claude Sonnet 5.5 from Anthropic.

How many models are evaluated on Protein Design — Sequence Generation?

2 models have been evaluated on the Protein Design — Sequence Generation benchmark, with 0 verified results and 2 self-reported results.

What categories does Protein Design — Sequence Generation cover?

Protein Design — Sequence Generation is categorized under science and biology. The benchmark evaluates text models.

Which model offers the best value on Protein Design — Sequence Generation?

Among models scoring within 10% of the leader, Claude Sonnet 5.5 from Anthropic is the cheapest, at $2.00 per million input tokens with a score of 0.510.

How recent are the Protein Design — Sequence Generation leaderboard results?

The Protein Design — Sequence Generation leaderboard was last updated in October 2026 and currently includes 2 evaluated models.