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Claude Opus 4 vs Mistral NeMo Instruct

Claude Opus 4 leads the LLM Stats Score 27.7 to -4.8. Mistral NeMo Instruct is 1379.3x cheaper per token.

Anthropic · Mistral AI · Updated for 2026

Which is better?

Claude Opus 4 leads the overall LLM Stats Score 27.7 to -4.8, ranking #139 overall.

On price, Mistral NeMo Instruct is roughly 1379.3x cheaper per token on a blended 3:1 input/output basis, which adds up quickly at production volume.

Claude Opus 4 also accepts a larger context window (200,000 input tokens), making it the stronger choice for long documents and large codebases.

Based on current LLM Stats indexes, shared benchmarks, pricing, and model metadata for 2026.

Choose Claude Opus 4

  • overall performance matters — it scores 27.7 and ranks #139 on LLM Stats
  • your work emphasizes reasoning — it leads those capability indexes
  • you process long inputs — it offers a 200,000 token context window
  • you want the most recent training data — it shipped May 2025

Choose Mistral NeMo Instruct

  • cost matters — it's about 1379.3x cheaper per token
  • you need open weights you can self-host or fine-tune

At a glance

The differences that matter most.

Core performance indexes
27.7
#139
-4.8
#353
27.7
#133
-5.0
#345
Cost, coverage & limits
Benchmark wins
Input price
$15.00 / M
$0.02 / M
Output price
$75.00 / M
$0.03 / M
Context window
200,000
131,072

Individual benchmarks

9 reported for Claude Opus 4 · 8 for Mistral NeMo Instruct

No common benchmarks found

Claude Opus 4 and Mistral NeMo Instructdon't have any common benchmark datasets to compare. They may have been evaluated on different testing suites.

Human preference

Blind head-to-head votes and playground preference scores

Pricing Analysis

Price comparison per million tokens

Mistral NeMo Instruct costs less

For input processing, Claude Opus 4 ($15.00/1M tokens) is 789.5x more expensive than Mistral NeMo Instruct ($0.02/1M tokens).

For output processing, Claude Opus 4 ($75.00/1M tokens) is 2500.0x more expensive than Mistral NeMo Instruct ($0.03/1M tokens).

In conclusion, Claude Opus 4 is more expensive than Mistral NeMo Instruct.*

* Using a 3:1 ratio of input to output tokens

Lowest available price from all providers
Sun Sep 20 2026 • llm-stats.com
Anthropic
Claude Opus 4
Input tokens$15.00
Output tokens$75.00
Best providerAnthropic
Mistral AI
Mistral NeMo Instruct
Input tokens$0.02
Output tokens$0.03
Best providerDeepinfra
Notice missing or incorrect data?Start an Issue

Context Window

Maximum input and output token capacity

Claude Opus 4 accepts 200,000 input tokens compared to Mistral NeMo Instruct's 131,072 tokens. Mistral NeMo Instruct can generate longer responses up to 131,072 tokens, while Claude Opus 4 is limited to 32,000 tokens.

Anthropic
Claude Opus 4
Input200,000 tokens
Output32,000 tokens
Mistral AI
Mistral NeMo Instruct
Input131,072 tokens
Output131,072 tokens
Sun Sep 20 2026 • llm-stats.com

Input capabilities

Documented input modalities across available providers

Claude Opus 4 supports multimodal inputs, whereas Mistral NeMo Instruct does not.

Claude Opus 4 can handle both text and other forms of data like images, making it suitable for multimodal applications.

Claude Opus 4

Text
Images
Audio
Video

Mistral NeMo Instruct

Text
Images
Audio
Video

License

Usage and distribution terms

Claude Opus 4 is licensed under a proprietary license, while Mistral NeMo Instruct uses Apache 2.0.

License differences may affect how you can use these models in commercial or open-source projects.

Claude Opus 4

Proprietary

Closed source

Mistral NeMo Instruct

Apache 2.0

Open weights

Release Timeline

When each model was launched

Claude Opus 4 was released on 2025-05-22, while Mistral NeMo Instruct was released on 2024-07-18.

Claude Opus 4 is 10 months newer than Mistral NeMo Instruct.

Claude Opus 4

May 22, 2025

1.3 years ago

10mo newer
Mistral NeMo Instruct

Jul 18, 2024

2.2 years ago

Knowledge Cutoff

When training data ends

Neither model specifies a knowledge cutoff date.

Unable to compare the recency of their training data.

No cutoff dates available

Provider Availability

Claude Opus 4 is available from Anthropic, Bedrock, Google. Mistral NeMo Instruct is available from DeepInfra, Google, Mistral AI.

Claude Opus 4

anthropic logo
Anthropic
Input Price:Input: $15.00/1MOutput Price:Output: $75.00/1M
bedrock logo
AWS Bedrock
Input Price:Input: $15.00/1MOutput Price:Output: $75.00/1M
google logo
Google
Input Price:Input: $15.00/1MOutput Price:Output: $75.00/1M

Mistral NeMo Instruct

deepinfra logo
Deepinfra
Input Price:Input: $0.02/1MOutput Price:Output: $0.03/1M
google logo
Google
Input Price:Input: $0.15/1MOutput Price:Output: $0.15/1M
mistral logo
Mistral
Input Price:Input: $0.15/1MOutput Price:Output: $0.15/1M
* Prices shown are per million tokens

Outputs Comparison

Notice missing or incorrect data?Start an Issue discussion

Judge for yourself.

Run your own prompts against Claude Opus 4 and Mistral NeMo Instruct side-by-side, then vote on the output you prefer.

Claude Opus 4
✓ Preferred
Mistral NeMo Instruct
Open in Playground

FAQ

Common questions about Claude Opus 4 vs Mistral NeMo Instruct.

Which is better, Claude Opus 4 or Mistral NeMo Instruct?

Claude Opus 4 leads the LLM Stats Score 27.7 to -4.8. Claude Opus 4 is made by Anthropic and Mistral NeMo Instruct is made by Mistral AI. The best choice depends on your use case — compare their capability indexes, individual benchmarks, pricing, and limits above.

How does Claude Opus 4 compare to Mistral NeMo Instruct in benchmarks?

Claude Opus 4 scores MMMLU: 88.8%, TAU-bench Retail: 81.4%, GPQA: 79.6%, MMMU (validation): 76.5%, AIME 2025: 75.5%. Mistral NeMo Instruct scores HellaSwag: 83.5%, Winogrande: 76.8%, TriviaQA: 73.8%, CommonSenseQA: 70.4%, MMLU: 68.0%.

Is Claude Opus 4 cheaper than Mistral NeMo Instruct?

Mistral NeMo Instruct is 789.5x cheaper for input tokens. Claude Opus 4 costs $15.00/M input and $75.00/M output via anthropic. Mistral NeMo Instruct costs $0.02/M input and $0.03/M output via deepinfra.

What are the context window sizes for Claude Opus 4 and Mistral NeMo Instruct?

Claude Opus 4 supports 200K tokens and Mistral NeMo Instruct supports 131K tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between Claude Opus 4 and Mistral NeMo Instruct?

Key differences include LLM Stats Score (27.7 vs -4.8), context window (200K vs 131K), input pricing ($15.00 vs $0.02/M), multimodal support (yes vs no), licensing (Proprietary vs Apache 2.0). See the full comparison above for benchmark-by-benchmark results.

Who makes Claude Opus 4 and Mistral NeMo Instruct?

Claude Opus 4 is developed by Anthropic and Mistral NeMo Instruct is developed by Mistral AI.