Model Comparison

Claude Opus 4.5 vs Mistral Medium 3.5Which is better in 2026?

Claude Opus 4.5 significantly outperforms across most benchmarks. Mistral Medium 3.5 is 3.3x cheaper per token.

Verdict: Claude Opus 4.5 vs Mistral Medium 3.5 — which is better?

Claude Opus 4.5 (by Anthropic) and Mistral Medium 3.5 (by Mistral AI) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.

Claude Opus 4.5 outperforms in 1 benchmarks (SWE-Bench Verified), while Mistral Medium 3.5 is better at 0 benchmarks. Claude Opus 4.5 significantly outperforms across most benchmarks.

On price, Mistral Medium 3.5 is roughly 3.3x cheaper per token on a blended 3:1 input/output basis, which adds up quickly at production volume.

Mistral Medium 3.5 also accepts a larger context window (256,000 input tokens), making it the stronger choice for long documents and large codebases.

Choose Claude Opus 4.5 if…

  • you want the strongest raw capability — it leads on 1 of 1 shared benchmarks

Choose Mistral Medium 3.5 if…

  • cost matters — it's about 3.3x cheaper per token
  • you process long inputs — it offers a 256,000 token context window
  • you want the most recent training data — it shipped Apr 2026
  • you need open weights you can self-host or fine-tune

Performance Benchmarks

Comparative analysis across standard metrics

1 benchmarks

Claude Opus 4.5 outperforms in 1 benchmarks (SWE-Bench Verified), while Mistral Medium 3.5 is better at 0 benchmarks.

Claude Opus 4.5 significantly outperforms across most benchmarks.

Sat Jun 13 2026 • llm-stats.com

Arena Performance

Human preference votes

Pricing Analysis

Price comparison per million tokens

Mistral Medium 3.5 costs less

For input processing, Claude Opus 4.5 ($5.00/1M tokens) is 3.3x more expensive than Mistral Medium 3.5 ($1.50/1M tokens).

For output processing, Claude Opus 4.5 ($25.00/1M tokens) is 3.3x more expensive than Mistral Medium 3.5 ($7.50/1M tokens).

In conclusion, Claude Opus 4.5 is more expensive than Mistral Medium 3.5.*

* Using a 3:1 ratio of input to output tokens

Lowest available price from all providers
Sat Jun 13 2026 • llm-stats.com
Anthropic
Claude Opus 4.5
Input tokens$5.00
Output tokens$25.00
Best providerAnthropic
Mistral AI
Mistral Medium 3.5
Input tokens$1.50
Output tokens$7.50
Best providerMistral
Notice missing or incorrect data?Start an Issue

Context Window

Maximum input and output token capacity

Mistral Medium 3.5 accepts 256,000 input tokens compared to Claude Opus 4.5's 200,000 tokens. Mistral Medium 3.5 can generate longer responses up to 256,000 tokens, while Claude Opus 4.5 is limited to 64,000 tokens.

Anthropic
Claude Opus 4.5
Input200,000 tokens
Output64,000 tokens
Mistral AI
Mistral Medium 3.5
Input256,000 tokens
Output256,000 tokens
Sat Jun 13 2026 • llm-stats.com

Input Capabilities

Supported data types and modalities

Both Claude Opus 4.5 and Mistral Medium 3.5 support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

Claude Opus 4.5

Text
Images
Audio
Video

Mistral Medium 3.5

Text
Images
Audio
Video

License

Usage and distribution terms

Claude Opus 4.5 is licensed under a proprietary license, while Mistral Medium 3.5 uses Modified MIT License.

License differences may affect how you can use these models in commercial or open-source projects.

Claude Opus 4.5

Proprietary

Closed source

Mistral Medium 3.5

Modified MIT License

Open weights

Release Timeline

When each model was launched

Claude Opus 4.5 was released on 2025-11-24, while Mistral Medium 3.5 was released on 2026-04-29.

Mistral Medium 3.5 is 5 months newer than Claude Opus 4.5.

Claude Opus 4.5

Nov 24, 2025

6 months ago

Mistral Medium 3.5

Apr 29, 2026

1 months ago

5mo newer

Knowledge Cutoff

When training data ends

Claude Opus 4.5 has a documented knowledge cutoff of 2025-03-31, while Mistral Medium 3.5's cutoff date is not specified.

We can confirm Claude Opus 4.5's training data extends to 2025-03-31, but cannot make a direct comparison without Mistral Medium 3.5's cutoff date.

Claude Opus 4.5

Mar 2025

Mistral Medium 3.5

Provider Availability

Claude Opus 4.5 is available from Anthropic. Mistral Medium 3.5 is available from Mistral AI.

Claude Opus 4.5

anthropic logo
Anthropic
Input Price:Input: $5.00/1MOutput Price:Output: $25.00/1M

Mistral Medium 3.5

mistral logo
Mistral
Input Price:Input: $1.50/1MOutput Price:Output: $7.50/1M
* Prices shown are per million tokens

Outputs Comparison

Notice missing or incorrect data?Start an Issue discussion

Key Takeaways

Higher SWE-Bench Verified score (80.9% vs 77.6%)
Larger context window (256,000 tokens)
Less expensive input tokens
Less expensive output tokens
Has open weights

Detailed Comparison

AI Model Comparison Table
Feature
Anthropic
Claude Opus 4.5
Mistral AI
Mistral Medium 3.5

FAQ

Common questions about Claude Opus 4.5 vs Mistral Medium 3.5.

Which is better, Claude Opus 4.5 or Mistral Medium 3.5?

Claude Opus 4.5 significantly outperforms across most benchmarks. Claude Opus 4.5 is made by Anthropic and Mistral Medium 3.5 is made by Mistral AI. The best choice depends on your use case — compare their benchmark scores, pricing, and capabilities above.

How does Claude Opus 4.5 compare to Mistral Medium 3.5 in benchmarks?

Claude Opus 4.5 scores Tau2 Telecom: 98.2%, MMMLU: 90.8%, Tau2 Retail: 88.9%, GPQA: 87.0%, SWE-Bench Verified: 80.9%. Mistral Medium 3.5 scores COLLIE: 95.8%, Tau3 Telecom: 91.4%, AIME 2025: 86.3%, SWE-Bench Verified: 77.6%, Tau3 Retail: 76.1%.

Is Claude Opus 4.5 cheaper than Mistral Medium 3.5?

Mistral Medium 3.5 is 3.3x cheaper for input tokens. Claude Opus 4.5 costs $5.00/M input and $25.00/M output via anthropic. Mistral Medium 3.5 costs $1.50/M input and $7.50/M output via mistral.

What are the context window sizes for Claude Opus 4.5 and Mistral Medium 3.5?

Claude Opus 4.5 supports 200K tokens and Mistral Medium 3.5 supports 256K tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between Claude Opus 4.5 and Mistral Medium 3.5?

Key differences include context window (200K vs 256K), input pricing ($5.00 vs $1.50/M), licensing (Proprietary vs Modified MIT License). See the full comparison above for benchmark-by-benchmark results.

Who makes Claude Opus 4.5 and Mistral Medium 3.5?

Claude Opus 4.5 is developed by Anthropic and Mistral Medium 3.5 is developed by Mistral AI.