Model Comparison
Claude Opus 4.5 vs Mistral Medium 3.5Which is better in 2026?
Claude Opus 4.5 significantly outperforms across most benchmarks. Mistral Medium 3.5 is 3.3x cheaper per token.
Verdict: Claude Opus 4.5 vs Mistral Medium 3.5 — which is better?
Claude Opus 4.5 (by Anthropic) and Mistral Medium 3.5 (by Mistral AI) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.
Claude Opus 4.5 outperforms in 1 benchmarks (SWE-Bench Verified), while Mistral Medium 3.5 is better at 0 benchmarks. Claude Opus 4.5 significantly outperforms across most benchmarks.
On price, Mistral Medium 3.5 is roughly 3.3x cheaper per token on a blended 3:1 input/output basis, which adds up quickly at production volume.
Mistral Medium 3.5 also accepts a larger context window (256,000 input tokens), making it the stronger choice for long documents and large codebases.
Choose Claude Opus 4.5 if…
- you want the strongest raw capability — it leads on 1 of 1 shared benchmarks
Choose Mistral Medium 3.5 if…
- cost matters — it's about 3.3x cheaper per token
- you process long inputs — it offers a 256,000 token context window
- you want the most recent training data — it shipped Apr 2026
- you need open weights you can self-host or fine-tune
Performance Benchmarks
Comparative analysis across standard metrics
Claude Opus 4.5 outperforms in 1 benchmarks (SWE-Bench Verified), while Mistral Medium 3.5 is better at 0 benchmarks.
Claude Opus 4.5 significantly outperforms across most benchmarks.
Arena Performance
Human preference votes
Pricing Analysis
Price comparison per million tokens
For input processing, Claude Opus 4.5 ($5.00/1M tokens) is 3.3x more expensive than Mistral Medium 3.5 ($1.50/1M tokens).
For output processing, Claude Opus 4.5 ($25.00/1M tokens) is 3.3x more expensive than Mistral Medium 3.5 ($7.50/1M tokens).
In conclusion, Claude Opus 4.5 is more expensive than Mistral Medium 3.5.*
* Using a 3:1 ratio of input to output tokens
Context Window
Maximum input and output token capacity
Mistral Medium 3.5 accepts 256,000 input tokens compared to Claude Opus 4.5's 200,000 tokens. Mistral Medium 3.5 can generate longer responses up to 256,000 tokens, while Claude Opus 4.5 is limited to 64,000 tokens.
Input Capabilities
Supported data types and modalities
Both Claude Opus 4.5 and Mistral Medium 3.5 support multimodal inputs.
They are both capable of processing various types of data, offering versatility in application.
Claude Opus 4.5
Mistral Medium 3.5
License
Usage and distribution terms
Claude Opus 4.5 is licensed under a proprietary license, while Mistral Medium 3.5 uses Modified MIT License.
License differences may affect how you can use these models in commercial or open-source projects.
Proprietary
Closed source
Modified MIT License
Open weights
Release Timeline
When each model was launched
Claude Opus 4.5 was released on 2025-11-24, while Mistral Medium 3.5 was released on 2026-04-29.
Mistral Medium 3.5 is 5 months newer than Claude Opus 4.5.
Nov 24, 2025
6 months ago
Apr 29, 2026
1 months ago
5mo newerKnowledge Cutoff
When training data ends
Claude Opus 4.5 has a documented knowledge cutoff of 2025-03-31, while Mistral Medium 3.5's cutoff date is not specified.
We can confirm Claude Opus 4.5's training data extends to 2025-03-31, but cannot make a direct comparison without Mistral Medium 3.5's cutoff date.
Mar 2025
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Provider Availability
Claude Opus 4.5 is available from Anthropic. Mistral Medium 3.5 is available from Mistral AI.
Claude Opus 4.5
Mistral Medium 3.5
Outputs Comparison
Key Takeaways
Claude Opus 4.5
View detailsAnthropic
Mistral Medium 3.5
View detailsMistral AI
Detailed Comparison
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FAQ
Common questions about Claude Opus 4.5 vs Mistral Medium 3.5.