Model Comparison

GPT-4o vs Mistral NeMo InstructWhich is better in 2026?

GPT-4o significantly outperforms across most benchmarks. Mistral NeMo Instruct is 29.2x cheaper per token.

Verdict: GPT-4o vs Mistral NeMo Instruct — which is better?

GPT-4o (by OpenAI) and Mistral NeMo Instruct (by Mistral AI) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.

GPT-4o outperforms in 1 benchmarks (MMLU), while Mistral NeMo Instruct is better at 0 benchmarks. GPT-4o significantly outperforms across most benchmarks.

On price, Mistral NeMo Instruct is roughly 29.2x cheaper per token on a blended 3:1 input/output basis, which adds up quickly at production volume.

Choose GPT-4o if…

  • you want the strongest raw capability — it leads on 1 of 1 shared benchmarks
  • you want the most recent training data — it shipped Aug 2024

Choose Mistral NeMo Instruct if…

  • cost matters — it's about 29.2x cheaper per token
  • you need open weights you can self-host or fine-tune
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Performance Benchmarks

Comparative analysis across standard metrics

1 benchmarks

GPT-4o outperforms in 1 benchmarks (MMLU), while Mistral NeMo Instruct is better at 0 benchmarks.

GPT-4o significantly outperforms across most benchmarks.

Wed Jun 17 2026 • llm-stats.com

Arena Performance

Human preference votes

Pricing Analysis

Price comparison per million tokens

Mistral NeMo Instruct costs less

For input processing, GPT-4o ($2.50/1M tokens) is 16.7x more expensive than Mistral NeMo Instruct ($0.15/1M tokens).

For output processing, GPT-4o ($10.00/1M tokens) is 66.7x more expensive than Mistral NeMo Instruct ($0.15/1M tokens).

In conclusion, GPT-4o is more expensive than Mistral NeMo Instruct.*

* Using a 3:1 ratio of input to output tokens

Lowest available price from all providers
Wed Jun 17 2026 • llm-stats.com
OpenAI
GPT-4o
Input tokens$2.50
Output tokens$10.00
Best providerAzure
Mistral AI
Mistral NeMo Instruct
Input tokens$0.15
Output tokens$0.15
Best providerGoogle
Notice missing or incorrect data?Start an Issue→

Context Window

Maximum input and output token capacity

Both models have the same input context window of 128,000 tokens. Mistral NeMo Instruct can generate longer responses up to 128,000 tokens, while GPT-4o is limited to 16,384 tokens.

OpenAI
GPT-4o
Input128,000 tokens
Output16,384 tokens
Mistral AI
Mistral NeMo Instruct
Input128,000 tokens
Output128,000 tokens
Wed Jun 17 2026 • llm-stats.com

Input Capabilities

Supported data types and modalities

GPT-4o supports multimodal inputs, whereas Mistral NeMo Instruct does not.

GPT-4o can handle both text and other forms of data like images, making it suitable for multimodal applications.

GPT-4o

Text
Images
Audio
Video

Mistral NeMo Instruct

Text
Images
Audio
Video

License

Usage and distribution terms

GPT-4o is licensed under a proprietary license, while Mistral NeMo Instruct uses Apache 2.0.

License differences may affect how you can use these models in commercial or open-source projects.

GPT-4o

Proprietary

Closed source

Mistral NeMo Instruct

Apache 2.0

Open weights

Release Timeline

When each model was launched

GPT-4o was released on 2024-08-06, while Mistral NeMo Instruct was released on 2024-07-18.

GPT-4o is 1 month newer than Mistral NeMo Instruct.

GPT-4o

Aug 6, 2024

1.9 years ago

2w newer
Mistral NeMo Instruct

Jul 18, 2024

1.9 years ago

Knowledge Cutoff

When training data ends

Neither model specifies a knowledge cutoff date.

Unable to compare the recency of their training data.

No cutoff dates available

Provider Availability

GPT-4o is available from Azure, OpenAI. Mistral NeMo Instruct is available from Google, Mistral AI.

GPT-4o

azure logo
Azure
Input Price:Input: $2.50/1MOutput Price:Output: $10.00/1M
openai logo
OpenAI
Input Price:Input: $2.50/1MOutput Price:Output: $10.00/1M

Mistral NeMo Instruct

google logo
Google
Input Price:Input: $0.15/1MOutput Price:Output: $0.15/1M
mistral logo
Mistral
Input Price:Input: $0.15/1MOutput Price:Output: $0.15/1M
* Prices shown are per million tokens

Outputs Comparison

Notice missing or incorrect data?Start an Issue discussion→

Key Takeaways

OpenAI
Supports multimodal inputs
Higher MMLU score (85.7% vs 68.0%)
Mistral AI
Less expensive input tokens
Less expensive output tokens
Has open weights

Detailed Comparison

AI Model Comparison Table
Feature
OpenAI
GPT-4o
Mistral AI
Mistral NeMo Instruct

FAQ

Common questions about GPT-4o vs Mistral NeMo Instruct.

Which is better, GPT-4o or Mistral NeMo Instruct?

GPT-4o significantly outperforms across most benchmarks. GPT-4o is made by OpenAI and Mistral NeMo Instruct is made by Mistral AI. The best choice depends on your use case — compare their benchmark scores, pricing, and capabilities above.

How does GPT-4o compare to Mistral NeMo Instruct in benchmarks?

GPT-4o scores AI2D: 94.2%, DocVQA: 92.8%, ChartQA: 85.7%, MMLU: 85.7%, CharXiv-D: 85.3%. Mistral NeMo Instruct scores HellaSwag: 83.5%, Winogrande: 76.8%, TriviaQA: 73.8%, CommonSenseQA: 70.4%, MMLU: 68.0%.

Is GPT-4o cheaper than Mistral NeMo Instruct?

Mistral NeMo Instruct is 16.7x cheaper for input tokens. GPT-4o costs $2.50/M input and $10.00/M output via azure. Mistral NeMo Instruct costs $0.15/M input and $0.15/M output via google.

What are the context window sizes for GPT-4o and Mistral NeMo Instruct?

GPT-4o supports 128K tokens and Mistral NeMo Instruct supports 128K tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between GPT-4o and Mistral NeMo Instruct?

Key differences include input pricing ($2.50 vs $0.15/M), multimodal support (yes vs no), licensing (Proprietary vs Apache 2.0). See the full comparison above for benchmark-by-benchmark results.

Who makes GPT-4o and Mistral NeMo Instruct?

GPT-4o is developed by OpenAI and Mistral NeMo Instruct is developed by Mistral AI.

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