Model Comparison

GPT-5.4 vs MedGemma 4B ITWhich is better in 2026?

Comparing GPT-5.4 and MedGemma 4B IT across benchmarks, pricing, and capabilities.

Verdict: GPT-5.4 vs MedGemma 4B IT — which is better?

GPT-5.4 (by OpenAI) and MedGemma 4B IT (by Google) are two of the AI models people compare most. Here is how they stack up on benchmarks, price and capabilities, and which one to pick in 2026.

Choose GPT-5.4 if…

  • you want the most recent training data — it shipped Mar 2026

Choose MedGemma 4B IT if…

  • you need open weights you can self-host or fine-tune
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Performance Benchmarks

Comparative analysis across standard metrics

No common benchmarks found

GPT-5.4 and MedGemma 4B ITdon't have any common benchmark datasets to compare. They may have been evaluated on different testing suites.

Arena Performance

Human preference votes

Context Window

Maximum input and output token capacity

Only GPT-5.4 specifies input context (1,000,000 tokens). Only GPT-5.4 specifies output context (128,000 tokens).

OpenAI
GPT-5.4
Input1,000,000 tokens
Output128,000 tokens
Google
MedGemma 4B IT
Input- tokens
Output- tokens
Wed Jun 24 2026 • llm-stats.com

Input Capabilities

Supported data types and modalities

Both GPT-5.4 and MedGemma 4B IT support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

GPT-5.4

Text
Images
Audio
Video

MedGemma 4B IT

Text
Images
Audio
Video

License

Usage and distribution terms

GPT-5.4 is licensed under a proprietary license, while MedGemma 4B IT uses Health AI Developer Foundations terms of use.

License differences may affect how you can use these models in commercial or open-source projects.

GPT-5.4

Proprietary

Closed source

MedGemma 4B IT

Health AI Developer Foundations terms of use

Open weights

Release Timeline

When each model was launched

GPT-5.4 was released on 2026-03-05, while MedGemma 4B IT was released on 2025-05-20.

GPT-5.4 is 10 months newer than MedGemma 4B IT.

GPT-5.4

Mar 5, 2026

3 months ago

9mo newer
MedGemma 4B IT

May 20, 2025

1.1 years ago

Knowledge Cutoff

When training data ends

Neither model specifies a knowledge cutoff date.

Unable to compare the recency of their training data.

No cutoff dates available

Outputs Comparison

Notice missing or incorrect data?Start an Issue discussion→

Key Takeaways

OpenAI
Larger context window (1,000,000 tokens)
Google
Has open weights

Detailed Comparison

AI Model Comparison Table
Feature
OpenAI
GPT-5.4
Google
MedGemma 4B IT

FAQ

Common questions about GPT-5.4 vs MedGemma 4B IT.

Which is better, GPT-5.4 or MedGemma 4B IT?

GPT-5.4 (OpenAI) and MedGemma 4B IT (Google) each have strengths in different areas. Compare their benchmark scores, pricing, context windows, and capabilities above to determine which fits your needs.

How does GPT-5.4 compare to MedGemma 4B IT in benchmarks?

GPT-5.4 scores Tau2 Telecom: 98.9%, ARC-AGI: 93.7%, Graphwalks BFS <128k: 93.0%, GPQA: 92.8%, Graphwalks parents <128k: 89.8%. MedGemma 4B IT scores MIMIC CXR: 88.9%, DermMCQA: 71.8%, PathMCQA: 69.8%, SlakeVQA: 62.3%, VQA-Rad: 49.9%.

What are the context window sizes for GPT-5.4 and MedGemma 4B IT?

GPT-5.4 supports 1.0M tokens and MedGemma 4B IT supports an unknown number of tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between GPT-5.4 and MedGemma 4B IT?

Key differences include licensing (Proprietary vs Health AI Developer Foundations terms of use). See the full comparison above for benchmark-by-benchmark results.

Who makes GPT-5.4 and MedGemma 4B IT?

GPT-5.4 is developed by OpenAI and MedGemma 4B IT is developed by Google.

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