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Claude Mythos 5.1 vs MedGemma 4B IT

Claude Mythos 5.1 leads the LLM Stats Score 45.1 to -4.5.

Anthropic · Google · Updated for 2026

Which is better?

Claude Mythos 5.1 leads the overall LLM Stats Score 45.1 to -4.5, ranking #31 overall.

Based on current LLM Stats indexes, shared benchmarks, pricing, and model metadata for 2026.

Choose Claude Mythos 5.1

  • overall performance matters — it scores 45.1 and ranks #31 on LLM Stats
  • your work emphasizes reasoning — it leads those capability indexes
  • you want the most recent training data — it shipped Sep 2026

Choose MedGemma 4B IT

  • you need open weights you can self-host or fine-tune

At a glance

The differences that matter most.

Claude Mythos 5.1
Anthropic
MedGemma 4B IT
Google
Core performance indexes
LLM Stats Score
45.1
#31
-4.5
#347
Reasoning
44.4
#34
-5.0
#344
Cost, coverage & limits
Benchmark wins
—
—
Input price
$10.00 / M
— / M
Output price
$50.00 / M
— / M
Context window
1,000,000
—

Individual benchmarks

1 reported for Claude Mythos 5.1 · 7 for MedGemma 4B IT

No common benchmarks found

Claude Mythos 5.1 and MedGemma 4B ITdon't have any common benchmark datasets to compare. They may have been evaluated on different testing suites.

Human preference

Blind head-to-head votes and playground preference scores

Context Window

Maximum input and output token capacity

Only Claude Mythos 5.1 specifies input context (1,000,000 tokens). Only Claude Mythos 5.1 specifies output context (128,000 tokens).

Anthropic
Claude Mythos 5.1
Input1,000,000 tokens
Output128,000 tokens
Google
MedGemma 4B IT
Input- tokens
Output- tokens
Tue Sep 08 2026 • llm-stats.com

Input capabilities

Documented input modalities across available providers

Both Claude Mythos 5.1 and MedGemma 4B IT support multimodal inputs.

They are both capable of processing various types of data, offering versatility in application.

Claude Mythos 5.1

Text
Images
Audio
Video

MedGemma 4B IT

Text
Images
Audio
Video

License

Usage and distribution terms

Claude Mythos 5.1 is licensed under a proprietary license, while MedGemma 4B IT uses Health AI Developer Foundations terms of use.

License differences may affect how you can use these models in commercial or open-source projects.

Claude Mythos 5.1

Proprietary

Closed source

MedGemma 4B IT

Health AI Developer Foundations terms of use

Open weights

Release Timeline

When each model was launched

Claude Mythos 5.1 was released on 2026-09-01, while MedGemma 4B IT was released on 2025-05-20.

Claude Mythos 5.1 is 16 months newer than MedGemma 4B IT.

Claude Mythos 5.1

Sep 1, 2026

1 weeks ago

1.3yr newer
MedGemma 4B IT

May 20, 2025

1.3 years ago

Knowledge Cutoff

When training data ends

Neither model specifies a knowledge cutoff date.

Unable to compare the recency of their training data.

No cutoff dates available

Outputs Comparison

Notice missing or incorrect data?Start an Issue discussion→

Judge for yourself.

Run your own prompts against Claude Mythos 5.1 and MedGemma 4B IT side-by-side, then vote on the output you prefer.

Claude Mythos 5.1
✓ Preferred
MedGemma 4B IT
Open in Playground

FAQ

Common questions about Claude Mythos 5.1 vs MedGemma 4B IT.

Which is better, Claude Mythos 5.1 or MedGemma 4B IT?

Claude Mythos 5.1 leads the LLM Stats Score 45.1 to -4.5. Claude Mythos 5.1 is made by Anthropic and MedGemma 4B IT is made by Google. The best choice depends on your use case — compare their capability indexes, individual benchmarks, pricing, and limits above.

How does Claude Mythos 5.1 compare to MedGemma 4B IT in benchmarks?

Claude Mythos 5.1 scores Terminal-Bench 4.0: 60.9%. MedGemma 4B IT scores MIMIC CXR: 88.9%, DermMCQA: 71.8%, PathMCQA: 69.8%, SlakeVQA: 62.3%, VQA-Rad: 49.9%.

What are the context window sizes for Claude Mythos 5.1 and MedGemma 4B IT?

Claude Mythos 5.1 supports 1.0M tokens and MedGemma 4B IT supports an unknown number of tokens. A larger context window lets you process longer documents, conversations, or codebases in a single request.

What are the main differences between Claude Mythos 5.1 and MedGemma 4B IT?

Key differences include LLM Stats Score (45.1 vs -4.5), licensing (Proprietary vs Health AI Developer Foundations terms of use). See the full comparison above for benchmark-by-benchmark results.

Who makes Claude Mythos 5.1 and MedGemma 4B IT?

Claude Mythos 5.1 is developed by Anthropic and MedGemma 4B IT is developed by Google.

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